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ea0089c16 | Clinical – Nuclear Medicine/Interventional Radiology/Imaging | NANETS2022

Clinical Utility of Somatostatin Receptor Positron Emission Tomography Imaging Biomarkers for Characterization of Meningioma Among Incidental Central Nervous System Lesions

Fortin Ensign, MD, PhD Shannon , Agarwal, MD Muskan , Klanderman, PhD Molly , Badawy, MB, BCh Mohamed , Halfdanarson, MD Thorvardur R. , Johnson, MD Derek R. , Bassam Sonbol, MD Mohamad , Kendi, MD Ayse T.

Background: Somatostatin receptor (SSTR) PET imaging is utilized with increasing frequency in the clinical management of neuroendocrine tumors. Incidental PET-avid CNS lesions are commonly noted and presumed to be meningiomas. However, SSTR PET lacks specificity for meningioma identification. This study aims to clarify the role of SSTR-based imaging for classification of incidental CNS lesionsMethods: Patients who had undergone both Ga-68-DOTATATE PET an...

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ea0089c21 | Clinical – Nuclear Medicine/Interventional Radiology/Imaging | NANETS2022

Characterizing Bone Metastases in Patients with Well-Differentiated Neuroendocrine Neoplasms Utilizing Ga68-DOTATATE PET

Coston, MD Tucker W. , Mahadevia, MBBS Himil J. , Plante, MD Marie M. , Accurso, MD Joseph M. , Sharma, MD, MBA Akash , Johnson, MD, PhD Geoffrey B. , Ashman, MD, PhD Jonathan B. , Tuba Kendi, MD Ayse , Bassam Sonbol, MD Mohamad , Hobday, MD Timothy J. , Halfdanarson, MD Thorvardur R. , Starr, DO Jason S.

Background: Tumors of neuroendocrine origin are a rare, heterogenous group of neoplasms. Neuroendocrine neoplasms (NENs) are categorized by site of origin, differentiation status, and by grade (Ki-67 expression and/or mitotic rate), with significant prognostic variability accordingly. These tumors frequently metastasize to bone, with reported incidence between 6-12% by older SSTR imaging. Our study evaluates patients with well-differentiated tumors of neuroendocrine origin to ...

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Endocrine Abstracts

Clinical Utility of Somatostatin Receptor Positron Emission Tomography Imaging Biomarkers for Characterization of Meningioma Among Incidental Central Nervous System Lesions

Characterizing Bone Metastases in Patients with Well-Differentiated Neuroendocrine Neoplasms Utilizing Ga68-DOTATATE PET

BiosciAbstracts